Protein

Structures: Tumor necrosis factor (P01375)

Accession
P01375 (TNFA_HUMAN)
Species
Homo sapiens (Human)
Length
233 amino acids (complete)
Source: UniProtKB


Domains and repeats

  1. Domain
1 50 100 150 200 233

Structural features and predictions

  1. no IPR
    Structural features
    1. CATH
    2. PDB
    3. SCOP
  1. no IPR
    Structural predictions
    1. MODBASE

Solved structures for this protein

ID Structure Description
4g3y Structure image for 4g3y Crystal structure of TNF-alpha in complex with Infliximab Fab fragment
3alq Structure image for 3alq Crystal structure of TNF-TNFR2 complex
3wd5 Structure image for 3wd5 Crystal structure of TNFalpha in complex with Adalimumab Fab fragment
3l9j Structure image for 3l9j Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
2zjc Structure image for 2zjc TNFR1 selectve TNF mutant; R1-6
2tun Structure image for 2tun CONFORMATIONAL CHANGES IN THE (ALA-84-VAL) MUTANT OF TUMOR NECROSIS FACTOR
2az5 Structure image for 2az5 Crystal Structure of TNF-alpha with a small molecule inhibitor
2zpx Structure image for 2zpx TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8
2e7a Structure image for 2e7a TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity
1tnf Structure image for 1tnf THE STRUCTURE OF TUMOR NECROSIS FACTOR-ALPHA AT 2.6 ANGSTROMS RESOLUTION. IMPLICATIONS FOR RECEPTOR BINDING
1a8m Structure image for 1a8m TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT
3it8 Structure image for 3it8 Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
5tsw Structure image for 5tsw HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
4tsv Structure image for 4tsv HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
4twt Structure image for 4twt Human TNFa dimer in complex with the semi-synthetic bicyclic peptide M21