Phenylalanine-4-hydroxylase (P00439)

P00439 (PH4H_HUMAN)
Homo sapiens (Human)
452 amino acids (complete)
Source: UniProtKB

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 452

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures

Residue annotation

  1. autoregulatory res...
  2. putative L-Phe bin...
  3. substrate binding ...
  4. cofactor binding s...
  5. metal binding site...

GO term prediction

Biological Process

GO:0006559 L-phenylalanine catabolic process
GO:0008152 metabolic process
GO:0009072 aromatic amino acid family metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004497 monooxygenase activity
GO:0004505 phenylalanine 4-monooxygenase activity
GO:0005506 iron ion binding
GO:0016597 amino acid binding
GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

Cellular Component

None predicted.