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Frizzled-8 (O93274)

Accession
O93274 (FZD8_XENLA)
Species
Xenopus laevis (African clawed frog)
Length
581 amino acids (complete)
Source: UniProtKB

Protein family membership

Homologous superfamilies

  1. Homologous superfamily
1 100 200 300 400 500 581

Domains and repeats

  1. Domain
1 100 200 300 400 500 581

Detailed signature matches

  1. Homologous superfamily IPR036790
    Frizzled cysteine-rich domain superfamily
    1. SSF63501
    2. G3DSA:1.10.20...
  2. Family IPR015526
    Frizzled/secreted frizzled-related protein
    1. PTHR11309
  3. Domain IPR020067
    Frizzled domain
    1. PS50038 (FZ)
    2. PF01392 (Fz)
    3. SM00063 (FRI)
  4. Domain IPR017981
    GPCR, family 2-like
    1. PS50261 (G_PROTEIN_...)
  5. Domain IPR000539
    Frizzled/Smoothened, transmembrane domain
    1. SM01330 (Frizzled)
    2. PR00489 (FRIZZLED)
    3. PF01534 (Frizzled)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.10...
  2. PTHR11309:SF126
  3. cd07461 (CRD_FZ8)
  4. cd15250 (7tmF_FZD8)
  5. mobidb-lite (disord...)

Residue annotation

  1. putative Wnt bindi...
  2. putative ligand bi...

GO term prediction

Biological Process

GO:0007166 cell surface receptor signaling pathway

Molecular Function

GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane