Protein

Tyrosine-protein kinase JAK2 (O60674)

Accession
O60674 (JAK2_HUMAN)
Species
Homo sapiens (Human)
Length
1,132 amino acids (complete)
Source: UniProtKB


Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 200 400 600 800 1000 1132

Detailed signature matches

Residue annotation

  1. putative phosphoin...
  2. putative peptide b...
  3. putative actin bin...
  4. phosphotyrosine bi...
  5. hydrophobic bindin...
  6. ATP binding site c...
  7. active site cd05078
  8. V617F mutation sit...
  9. polypeptide substr...
  10. activation loop (A...
  11. ATP binding site c...
  12. active site cd14205
  13. polypeptide substr...
  14. activation loop (A...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0035556 intracellular signal transduction

Molecular Function

GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0042393 histone binding

Cellular Component

GO:0005856 cytoskeleton
GO:0016020 membrane