Protein Focus

Protein Focus (formally known as Protein of the Month) explores the function and family relationships of selected proteins from the InterPro database, aiming at a general audience. Each article introduces a different protein, exploring its biological function as it relates to other members of the protein family, examining common domain architectures and their biological distribution, and tying it in to a broader perspective on how the protein impacts today's medicine and the environment. The articles also serve as an introduction to the use of the InterPro database, exploring the relevant InterPro entries for each featured protein in detail, and relating them to the biological information discussed in the article. Links are provided to the PDB's Molecule of the Month, where the structural features of the proteins are explored in detail, and, when applicable, to the EXPASY Protein Spotlight to gain another view of the featured proteins.

Follow the links below to explore any of the proteins in the archive.

2011	September: Killer toxin Protein (KP4) (PDF) February: Chemokine receptor type 4 (CXCR4) (PDF)
2009	January: Collagen
2007	June: Fatty Acid Synthase May: Aconitase April: Clathrin March: Zinc fingers February: RNA exosomes January: Importins
2006	December: Transposase November: Fibrinogen October: Cytochrome P450 September: Elongation Factors August: AAA ATPases July: Amyloid-beta Precursor Protein June: Luciferase May: Glucose Oxidase and Biosensors April: Bird Flu Haemagglutinin March: Tissue_Factor February: Alpha-amylase January: DNA topoisomerase
2005	December: ATP Synthase November: Acetylcholine Receptors October: Haemoglobin September: Cholera Toxin August: TRK Receptors July: TATA-box Binding Proteins June: Carotenoid oxygenase May: Sm Ribonucleoproteins April: Kinesin March: T Cell receptors February: Major Histocompatibility Complex (MHC) January: Phenylalanine Hydroxylase
2004	December: Ubiquitin November: Photosystem II October: G Proteins September: Catalase August: Caspases July: DNA Ligase IV June: Snake Venom: Bungarotoxins May: Serpins: alpha-1 antitrypsin April: Growth Hormone Receptors March: Calcium Pumps February: Enzymes of Glycolysis January: Carbonic Anhydrase
2003	December: Catabolite Activator Protein November: Simian Virus 40 October: Trypsin September: Oestrogen receptors August: Calmodulin July: SRC, proto-oncogene tyrosine-protein kinase June: Green fluorescent protein

Contact

For information, comments or suggestions about Protein Focus, please email us at interhelp@ebi.ac.uk