InterProScan logo extended InterProScan is the software package that allows sequences (protein and nucleic) to be scanned against InterPro's signatures. Signatures are predictive models, provided by several different databases, that make up the InterPro consortium.

Download the latest version

InterProScan 5.16-55.0
Linux, 32 bit or 64 bit (64 bit recommended) - System requirements

  • Linux, 32 bit or 64 bit
  • Perl
  • Python 2.7. or greater
  • Java 6,7 (but NOT Java 8)
  • Oracle's Java JDK/JRE version 6u4 and higher

  • Computer with 2 cores and 4 GB of RAM
  • 400MB of available disk space
  • Screen resolution of 1024x768 or greater is required
  • Broadband Internet connection

There are no versions planned for Windows or Apple operating systems. This is due to constraints in the various third-party binaries that InterProScan runs.

Download InterProScan
Version 5.16-55.0 - 64 bit Linux - 3.9GB

Older versions of InterProScan are not supported anymore. We highly recommend you to update to the latest version.
Click here to download the 32 bit Linux version (MD5:349dbc78a4b0dd626667a614238f20a2) of InterProScan. For more information on downloading, installing and running InterProScan please see the InterProScan wiki.

Web services

Programmatic access to InterProScan is possible via a number of different web service protocols, that allow up to 30 sequences to be analysed per request.


We provide access to InterProScan via RESTful services.



We also provide access to InterProScan via SOAP-based web services.


Web based tools

Web access using the sequence search box on the InterPro website (homepage or under /search/sequence), for the analysis of single protein sequences in FASTA format with a maximum length of 40,000 amino acid long.

Source code

You can find, clone, and download the full InterProScan source code on the Github repository, available under


You can view the changelog archive. Previous releases can be found in the release archive section.


The InterProScan software is distributed under the open source Apache license, as are the included scanning tools (except SignalP and TMHMM). Therefore, you do not need a special license for commercial use but please cite the resource and keep the Copyright statement with your installation.

Follow us & reporting bugs

If you want to get updates on InterProScan, you can subscribe to the interproscan-announce mailing list or just follow InterPro on Twitter @InterProDB.

If you want to submit a question or report a bug, please contact us by email or contact us using the EBI form, providing as much information as possible so that we can recreate the problem.

Related Publications

InterProScan 5 user's guide cover InterProScan 5 user's guide
Full documentation to help on installation, configuration, migration.

Need more help?

If you need more info on InterProScan, you can either look at the:

Wiki documentation page
Training material
or contact us directly with your question.