Domain

Reverse transcriptase, RNase H-like domain (IPR041373)

Short name: RT_RNaseH

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

DNA polymerase and ribonuclease H (RNase H) activities allow reverse transcriptases to convert the single-stranded retroviral RNA genome into double-stranded DNA, which is integrated into the host chromosome during infection [PMID: 15130474]. This entry represents an RNase H-like domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam