Chorion-specific transcription factor GCM (IPR039791)

Short name: GCM

Overlapping homologous superfamilies

Family relationships



GCM transcription factors are a family of proteins which contain a GCM motif. They bind specific sequences on gene promoters and activate their transcription. Human GCM1 is involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes [PMID: 10542267, PMID: 18160678]. Fruit fly GCM determines the choice between glial and neuronal fates [PMID: 7553843].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.