Transmembrane channel-like protein (IPR038900)

Short name: TMC

Overlapping homologous superfamilies


Family relationships



This entry represents the transmembrane channel-like (TMC) protein family. TMC proteins are thought to have important cellular roles, and may be modifiers of ion channels or transporters [PMID: 12812529]. Mutations in these genes are implicated in a number of human conditions, such as deafness and epidermodysplasia verruciformis [PMID: 12906855].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005887 integral component of plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.