E3 ubiquitin-protein ligase RNF186 (IPR038878)

Short name: RNF186

Overlapping homologous superfamilies

Family relationships



RNF186 is a RING finger E3 ligase that regulates ER stress-mediated apoptosis [PMID: 23896122]. RNF186 is an ulcerative colitis-associated gene that is thought to contribute to gut homeostasis by controlling ER stress in colonic epithelia [PMID: 27381925].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0061630 ubiquitin protein ligase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.