Homologous Superfamily

PAW domain superfamily (IPR038680)

Short name: PAW_sf

Overlapping entries


The PAW domain (present in PNGases and other worm proteins) is found as a single copy at the C terminus of metazoan peptide:N-glycanase (PNGase) and in multiple copies in hypothetical Caenorhabditis elegans proteins peptide:N-glycanases (PNGases) [PMID: 11779830]. The C-terminal PAW domain of PNGase binds to the mannose moieties of N-linked oligosaccharide chains [PMID: 17088551].

The PAW domain is a slightly elongated molecule and displays a beta-sandwich architecture, which is composed of two layers, containing nine and eight antiparallel beta-strands, respectively, and three additional short helices [PMID: 17088551].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.