Homologous Superfamily

MraZ superfamily (IPR038619)

Short name: MraZ_sf

Overlapping entries

Description

The gene encoding MraZ is often found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc. In E. coli, MraZ is a DNA-binding transcription factor [PMID: 24659771]. It acts as a repressor of Pmra, which is a promoter for mraZ and mraW. It also regulates the expression of genes outside the dcw cluster. Overproduction of Escherichia coli MraZ inhibits cell division [PMID: 24659771].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D