Homologous Superfamily

Daxx, N-terminal domain superfamily (IPR038298)

Short name: Daxx_N_sf

Overlapping entries


The Daxx protein (also known as death domain-associated protein 6) is thought to play a role in apoptosis. Daxx forms a complex with Axin [PMID: 11225842]. Daxx is a scaffold protein shown to play diverse roles in transcription and cell cycle regulation. This N-terminal domain folds into a left-handed four-helix bundle (H1, H2, H4, H5) that binds to the N-terminal residues of the tumour-suppressor Rassf1C [PMID: 21134643].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.