Homologous Superfamily

DGK type I, N-terminal domain superfamily (IPR038199)

Short name: DGK_typeI_N_sf

Overlapping entries


This superfamily represents a domain found at the N terminus of the EF-hand domain of the type I diacylglycerol kinases (DGKs). DGKs phosphorylate diacylglycerol (DAG) to produce phosphatidic acid (PA) and play an important role in signal transduction by modulating the balance between these signalling lipids. DGKs can be classified into five types. Proteins containing this domain are EF-hand domain containing type I DGKs, including DGK-alpha, beta and gamma [PMID: 22984004].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.