Polycomb group RING finger protein 6 (IPR038037)

Short name: PCGF6

Overlapping homologous superfamilies


Family relationships



Polycomb group RING finger protein 6 (PCGF6 or MBLR) is a transcriptional repressor [PMID: 12167161]. It may activate KDM5D histone demethylase, which modulates the levels of histone H3K4Me3 [PMID: 17320162]. PCGF6 is a component of the Polycomb group (PcG) multiprotein PRC1-like complex [PMID: 21282530], in which it regulates RNF2 ubiquitin ligase activity [PMID: 26151332], and the complex [PMID: 12004135]. PCGF6 contains a RING-type zinc finger.

GO terms

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0035102 PRC1 complex
GO:0031519 PcG protein complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.