Family

Alpha-2-macroglobulin receptor-associated protein (IPR038003)

Short name: A2-macroglobuin_RAP

Overlapping homologous superfamilies

Family relationships

None.

Description

The alpha-2-macroglobulin receptor-associated protein (RAP) is a intracellular glycoprotein that binds to the alpha-2-macroglobulin receptor (a2MR), also known as low-density lipoprotein receptor-related protein (LRP), and other members of the low density lipoprotein receptor family. The protein inhibits binding of all currently known ligands of these receptors [PMID: 7774585, PMID: 8654360, PMID: 7538675].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0050750 low-density lipoprotein particle receptor binding
GO:0048019 receptor antagonist activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER