Family

Nucleoside diphosphate kinase 6 (IPR037994)

Short name: NDPk6

Overlapping homologous superfamilies

Family relationships

Description

Nucleoside diphosphate kinase 6 (NDPk6, also known as NM23-H6) is expressed mainly in mitochondria, but also found at a lower level in most tissues [PMID: 10618642]. NDPk6 has all nine residues considered crucial for enzyme structure and activity, and has been found to have NDP kinase activity [PMID: 10453732]. It may play a role in cell growth and cell cycle progression. The nm23-H6 gene locus has been implicated in a variety of malignant tumours [PMID: 15726650].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004550 nucleoside diphosphate kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD