1,4-alpha-glucan-branching enzyme (IPR037439)

Short name: Branching_enzy

Overlapping homologous superfamilies

Family relationships


This entry consists of glycogen branching enzyme GlgB from bacteria and GBE1 from eukaryotes, which are responsible for the transfer of chains of alpha(1,4)-linked glucosyl residues to other similar chains (in new alpha-(1,6) linkages) in the biosynthesis of glycogen [PMID: 7862674]. GlgB is responsible for the degree of alpha(1,6) branch linkages found in polysaccharides [PMID: 2959476]. GBE1 is required for normal glycogen accumulation in animals [PMID: 8463281, PMID: 26199317]. Deficiency in GBE1 results in glycogen storage disease type IV [PMID: 8613547].

GO terms

Biological Process

GO:0005978 glycogen biosynthetic process

Molecular Function

GO:0003844 1,4-alpha-glucan branching enzyme activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.