Family

Kinetochore scaffold 1 (IPR037388)

Short name: Blinkin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

The KMN network (for KNL1, MIS12 and NDC80 complexes) is a hub for signalling at the outer kinetochore [PMID: 17129783] that acts as a receptor for both microtubules and checkpoint proteins [PMID: 25601404]. Kinetochore scaffold 1, also known as Blinkin or KNL1, is a component of the KMN network. It is required to localize a subset of outer kinetochore proteins and is essential for chromosome segregation [PMID: 17981135, PMID: 18045986].

GO terms

Biological Process

GO:0008608 attachment of spindle microtubules to kinetochore
GO:0034501 protein localization to kinetochore

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER