Pleckstrin-2, DEP domain (IPR037369)

Short name: PLEK2_DEP

Overlapping homologous superfamilies

Domain relationships

  • DEP domain (IPR000591)
    • Pleckstrin-2, DEP domain (IPR037369)


Pleckstrin 2 is found in a wide variety of cell types, which suggest a more general role in signaling than pleckstrin 1 [PMID: 10419454]. Pleckstrin-like proteins contain a central DEP domain, flanked by 2 PH (pleckstrin homology) domains.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.