Aminopyrrolnitrin oxygenase PrnD, Rieske domain (IPR037338)

Short name: PrnD_Rieske

Overlapping homologous superfamilies

Domain relationships


This entry represents the N-terminal Rieske domain of the oxygenase alpha subunit of aminopyrrolnitrin oxygenase (PrnD). PrnD is a novel Rieske N-oxygenase that catalyzes the final step in the pyrrolnitrin biosynthetic pathway, the oxidation of the amino group in aminopyrrolnitrin to a nitro group, forming the antibiotic pyrrolnitrin. The biosynthesis of pyrrolnitrin is one of the best examples of enzyme-catalyzed arylamine oxidation. Although arylamine oxygenases are widely distributed within the microbial world and used in a variety of metabolic reactions, PrnD represents one of only two known examples of arylamine oxygenases or N-oxygenases involved in arylnitro group formation, the other being AurF involved in aureothin biosynthesis [PMID: 16150698, PMID: 16342311].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0051537 2 iron, 2 sulfur cluster binding
GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.