Homologous Superfamily

Kynurenine formamidase superfamily (IPR037175)

Short name: KFase_sf

Overlapping entries


Kynurenine formamidase catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation [PMID: 14592712]. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form a part of the active site.

Structurally, it contains a mixed beta-sheet close barrel fold.

GO terms

Biological Process

GO:0019441 tryptophan catabolic process to kynurenine

Molecular Function

GO:0004061 arylformamidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.