Homologous Superfamily

Histone acetyl transferase 1, N-terminal domain superfamily (IPR037113)

Short name: Hat1_N_sf

Overlapping entries


This entry represents the N-terminal domain superfamily of the structure of histone acetyl transferase HAT1. It is often found in association with the C-terminal part of IPR000182. It seems to be motifs C and D of the structure. Histone acetyltransferases (HATs) catalyse the transfer of an acetyl group from acetyl-CoA to the lysine E-amino groups on the N-terminal tails of histones. HATs are involved in transcription since histones tend to be hyper-acetylated in actively transcribed regions of chromatin, whereas in transcriptionally silent regions histones are hypo-acetylated [PMID: 9175471].

GO terms

Biological Process

GO:0006325 chromatin organization

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.