Homologous Superfamily

RBP-J/Cbf11/Cbf12, DNA binding domain superfamily (IPR037095)

Short name: RBP-J/Cbf11/Cbf12_DNA-bd_sf

Overlapping entries


This domain superfamily is found in RBP-J from human and Cbf11/Cbf12 from fission yeast. These proteins function as transcription factors [PMID: 19101542, PMID: 23303788]. This domain adopts a beta sandwich structure, with nine strands in two beta-sheets, in a Greek-key topology, and allow for DNA binding [PMID: 15297877].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.