Homologous Superfamily

Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily (IPR037092)

Short name: FlavoCytC_S_DH_flav-bd_sf

Overlapping entries


This entry represents the flavin-binding domain superfamily of flavocytochrome c sulphide dehydrogenase (FCSD), enzymes found in sulphur-oxidising bacteria such as the purple phototrophic bacteria Chromatium vinosum [PMID: 7939681, PMID: 15544340]. These enzymes are complexes of flavoprotein and a dihaem cytochrome that carry out hydrogen sulphide-dependent cytochrome C reduction. The dihaem cytochrome folds into two domains, each of which resembles mitochondrial cytochrome c, with the two haem groups bound to the interior of the subunit. The flavoprotein subunit has a glutathione reductase-like fold consisting of a beta(3,4)-alpha(3) core, and an alpha+beta sandwich. The active site of the flavoprotein subunit contains a catalytically important disulphide bridge located above the pyrimidine portion of the flavin ring [PMID: 7939681]. Electrons are transferred from the flavin to one of the haem groups in the cytochrome. This entry represents a flavoprotein domain required for binding to flavin, and subsequent electron transfer.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0050660 flavin adenine dinucleotide binding
GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.