Homologous Superfamily

NEDD8-activating enzyme E1 catalytic subunit, C-terminal (IPR037078)

Short name: NEDD8-ac_enz1_catalyticsu_C

Overlapping entries


E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The protein resembles ubiquitin, and recruits the catalytic core of the E2 enzyme Ubc12 in a similar manner to that in which ubiquitin interacts with ubiquitin binding domains [PMID: 15694336].

GO terms

Biological Process

GO:0045116 protein neddylation

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.