Homologous Superfamily

DNA primase, catalytic core, N-terminal domain superfamily (IPR037068)

Short name: DNA_primase_core_N_sf

Overlapping entries


DNA primase (EC:2.7.7) is a nucleotidyltransferase which synthesizes the oligoribonucleotide primers required for DNA replication on the lagging strand of the replication fork. It can also prime the leading strand and has been implicated in cell division [PMID: 8294018]. Primases comprise three domains: a zinc-binding domain (N-terminal) that is responsible for template recognition, a polymerase domain (catalytic core), and a domain that interacts with the replicative helicase, DnaB (C-terminal).

This superfamily represents the N-terminal part of the catalytic core domain of DNA primases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.