Homologous Superfamily

Epstein Barr virus nuclear antigen-1, DNA-binding domain superfamily (IPR037007)

Short name: EBNA1_DNA-bd_sf

Overlapping entries


The Epstein-Barr virus (strain GD1) nuclear antigen 1 (EBNA1) binds to and activates DNA replication from the latent origin of replication. The crystal structure of the DNA-binding and dimerization domains were solved [PMID: 7553871], and it was found that EBNA1 appears to bind DNA via two independent regions, the core and the flanking DNA-binding domains. This DNA-binding domain has a ferredoxin-like fold.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0042025 host cell nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.