Homologous Superfamily

DNA Primase, CHC2-type zinc finger (IPR036977)

Short name: DNA_primase_Znf_CHC2

Overlapping entries


DNA primase (EC:2.7.7) is a nucleotidyltransferase which synthesizes the oligoribonucleotide primers required for DNA replication on the lagging strand of the replication fork. It can also prime the leading strand and has been implicated in cell division [PMID: 8294018]. Primases comprise three domains: a zinc-binding domain (N-terminal) that is responsible for template recognition, a polymerase domain (catalytic core), and a domain that interacts with the replicative helicase, DnaB (C-terminal).

This superfamily describes the zinc-binding domain of DNA primase, which belongs to the zinc ribbon type [PMID: 10745010].

GO terms

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.