Homologous Superfamily

Pheromone/general odorant binding protein superfamily (IPR036728)

Short name: PBP_GOBP_sf

Overlapping entries


The olfactory receptors of terrestrial animals exist in an aqueous environment, yet detect odorants that are primarily hydrophobic. The aqueous solubility of hydrophobic odorants is thought to be greatly enhanced via odorant binding proteins which exist in the extracellular fluid surrounding the odorant receptors [PMID: 2010751]. This superfamily is composed of pheromone binding proteins (PBP), which are male-specific and associate with pheromone-sensitive neurons and general-odorant binding proteins (GOBP).

Members of this superfamily has an EF Hand-like fold, which has a core of four helices and an array of two opened hairpins. The N-terminal extension of these domains, containing a few short helices, forms a flexible lid for the binding cavity.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005549 odorant binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.