Homologous Superfamily

VSV matrix superfamily (IPR036711)

Short name: VSV_matrix_sf

Overlapping entries


This superfamily consists of several Vesiculovirus matrix proteins. The matrix (M) protein of vesicular stomatitis virus (VSV) expressed in the absence of other viral components causes many of the cytopathic effects of VSV, including an inhibition of host gene expression and the induction of cell rounding. It has been shown that M protein also induces apoptosis in the absence of other viral components. It is thought that the activation of apoptotic pathways causes the inhibition of host gene expression and cell rounding by M protein [PMID: 12692256]. Structurally, the M protein consists of a single globular domain [PMID: 12065402].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005198 structural molecule activity

Cellular Component

GO:0019031 viral envelope

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.