Homologous Superfamily

DinI-like superfamily (IPR036687)

Short name: DinI-like_sf

Overlapping entries


This superfamily of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity [PMID: 12626715]. The structure of DinI is known [PMID: 11152126].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.