Homologous Superfamily

CO dehydrogenase flavoprotein, C-terminal domain superfamily (IPR036683)

Short name: CO_DH_flav_C_dom_sf

Overlapping entries


Proteins containing this domain form structural complexes with other known families, such as IPR008274 and IPR001041. The carbon monoxide (CO) dehydrogenase of Oligotropha carboxidovorans is a heterotrimeric complex composed of a apoflavoprotein, a molybdoprotein, and an iron-sulphur protein. It can be dissociated with sodium dodecylsulphate [PMID: 10636886]. CO dehydrogenase catalyzes the oxidation of CO according to the following equation [PMID: 11076018]: CO + H2O = CO2 + 2e + 2H+

Subunit S represents the iron-sulphur protein of CO dehydrogenase and is clearly divided into a C- and an N-terminal domain, each binding a [2Fe-2S] cluster [PMID: 10430865].

The structure of the C-terminal domain has a beta(3,4)-alpha(3) fold arranged in an alpha+beta sandwich.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.