Homologous Superfamily

N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily (IPR036505)

Short name: Amidase/PGRP_sf

Overlapping entries


This entry represents a domain found in N-acetylmuramoyl-L-alanine amidases from bacteria and peptidoglycan recognition proteins (PGRP). PGRPs are ubiquitous proteins involved in innate immunity, conserved from insects to mammals. They have antibactericidal activity [PMID: 9707603, PMID: 12649138]. PGRPs have at least one of these domains homologous to bacteriophage and bacterial type 2 amidases [PMID: 16930467]. Some PGRPs have been shown to be N-acetylmuramoyl-L-alanine amidases [PMID: 14506276, PMID: 12496260].

GO terms

Biological Process

GO:0009253 peptidoglycan catabolic process

Molecular Function

GO:0008745 N-acetylmuramoyl-L-alanine amidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.