Homologous Superfamily

SpoA-like superfamily (IPR036429)

Short name: SpoA-like_sf

Overlapping entries


Proteins of the surface presentation of antigen (SpoA) group are involved in a secretory pathway responsible for the surface presentation of invasion plasmid antigen needed for the entry of Salmonella and other species into mammalian cells [PMID: 1447979, PMID: 8885278].They could play a role in preserving the translocation competence of the IPA antigens and are required for secretion of the three IPA proteins [PMID: 1312536].

The SpoA structure is composed of a segment-swapped dimer forming two identical conjoint barrels fold and is topologically similar to the FMN-binding split barrel.

The C-terminal region of flagellar motor switch proteins FliN and FliM is also included in this entry.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.