Homologous Superfamily

YaeB, N-terminal domain superfamily (IPR036414)

Short name: YaeB_N_sf

Overlapping entries


TrmO (also known as TsaA or YaeB) is a RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs. It has a unique single-sheeted beta-barrel structure and represent a new category of AdoMet-dependent methyltransferases [PMID: 25063302].

The crystal structure of Haemophilus influenzae YaeB has been solved. In addition to the N-terminal beta-barrel methyltransferase domain it has a C-terminal domain containing the conserved sequence motif DPRxxY [PMID: 25063302]. This superfamily describes the N-terminal domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.