Homologous Superfamily

Class II aldolase/adducin N-terminal domain superfamily (IPR036409)

Short name: Aldolase_II/adducin_N_sf

Overlapping entries

Description

This entry represents the alpha/beta/alpha domain found in class II aldolases and in adducin (usually at the N terminus of adducin). Proteins containing this domain include: rhamnulose-1-phosphate aldolase (EC:4.1.2.19), L-fuculose phosphate aldolase (EC:4.1.2.17) [PMID: 8515438, PMID: 8676381] that is involved in the third step in fucose metabolism, L-ribulose- 5-phosphate 4-epimerase (EC:5.1.3.4) involved in the third step of L-arabinose catabolism, a probable sugar isomerase SgbE and the metazoan adducins, which have not been ascribed any enzymatic function but which play a role in cell membrane cytoskeleton organisation [PMID: 1840603].

This entry also includes the methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway. This pathway allows methylthioadenosine, left over from polyamine biosynthesis, to be recycled to methionine.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY
GENE3D