Homologous Superfamily

Aminotransferase-like, PLP-dependent enzymes (IPR036038)

Short name: Aminotransferase-like

Overlapping entries

Description

Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [PMID: 1644759] into subfamilies.

The D-amino acid transferases (D-AAT) are required by bacteria to catalyse the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids [PMID: 7626635, PMID: 9163511].

D-aminoacid aminotransferase is a homo hexamer with D3 symmetry, folded into two domains [PMID: 9163511]. The first one has a beta3-alpha2-beta2 fold, while the second one has an alpha/beta fold.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY