Homologous Superfamily

Gated mechanosensitive channel (IPR036019)

Short name: Gated_MS_channel

Overlapping entries


Mechanosensitive ion channels (MscL) play a critical role in transducing physical stresses at the cell membrane into an electrochemical response. MscL is a protein which forms a channel organised as a homopentamer, with each subunit containing two transmembrane regions [PMID: 9856938]. Prokaryotes harbor a large-conductance mechanosensitive channel (gene mscL) that opens in response to stretch forces in the membrane lipid bilayer and may participate in the regulation of osmotic pressure changes within the cell [PMID: 9632260].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.