116kDa U5 small nuclear ribonucleoprotein component, C-terminal (IPR035655)

Short name: U5-116kDa_C

Overlapping homologous superfamilies


Domain relationships


This domain is found in the C-terminal portion of the spliceosomal human 116kDa U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116kDa), and its yeast counterpart Snu114p. This domain is homologous to the C-terminal domain of the eukaryotic translational elongation factor EF-2 [PMID: 9233818]. Yeast Snu114p is a GTPase component of U5 snRNP essential for pre-mRNA splicing [PMID: 15911574, PMID: 12736260, PMID: 16540695].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.