Domain

GTP binding protein 1-like, GTP-binding domain (IPR035531)

Short name: GTPBP1-like

Overlapping homologous superfamilies

Domain relationships

Description

This GTP-binding domain is found in mammalian GTP binding protein 1 (GTPBP1), GTPBP2, and nematode homologues AGP-1 and CGP-1 [PMID: 11054535].

Even though GTPBP1 has a GTP-binding domain, it has not been reported to have GTPase activity. GTPBP1 is thought to modulate mRNA decay by destabilizing the interactions between the RBPs and the cytoplasmic exosome using a GTP-binding-dependent mechanism [PMID: 21515746].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD