Domain

Bifunctional phosphoglucose/phosphomannose isomerase, SIS domain 1 (IPR035484)

Short name: SIS_PGI/PMI_1

Overlapping homologous superfamilies

None.

Domain relationships

  • Sugar isomerase (SIS) (IPR001347)
    • Bifunctional phosphoglucose/phosphomannose isomerase, SIS domain 1 (IPR035484)

Description

Bifunctional phosphoglucose/phosphomannose isomerase has both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to fructose 6-phosphate, and mannose 6-phosphate to fructose 6-phosphate, respectively, at an equal rate [PMID: 15290326, PMID: 14551194].

This protein contains two SIS (Sugar ISomerase) domains. This entry represents the first SIS domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD