Domain

Nrap protein, domain 3 (IPR035368)

Short name: Nrap_D3

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents a conserved domain found in Nrap.

Nucleolar RNA-associated proteins (Nrap) are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [PMID: 11895476].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam