Domain

Starch-binding domain-containing protein 1, CBM20 domain (IPR034838)

Short name: CBM20_genethonin_1

Domain relationships

Description

Starch-binding domain-containing protein 1 (STBD1), also known as Genethonin-1, is predicted to contain a hydrophobic N terminus, that allows it to associate with a cellular membrane structure, and a C-terminal CBM20 glycan binding domain. STBD1 is involved in glycogen metabolism by binding to glycogen and anchoring it to membranes, thereby affecting its cellular localization and its intracellular trafficking to lysosomes [PMID: 20810658]. It has also been reported to interact with a known autophagy protein GABARAPL1, a member of the Atg8 family [PMID: 21893048].

The CBM20 domain of STBD1 is crucial for its stability and ability to interact with glycogen-associated proteins [PMID: 24837458].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:2001069 glycogen binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD