Family

Endolysin lambda type (IPR034691)

Short name: Endolysin_lambda_type

Overlapping homologous superfamilies

Family relationships

Description

This family includes endolysin from bacteriophage lambda and its relatives. Endolysin is a lysozyme that hydrolyses the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in the bacterial cell wall peptidoglycan [PMID: 6448076]. Endolysin and the cell membrane pore-forming proteins holin and spanin act together to bring about host cell lysis and release of virus particles [PMID: 24113139].

GO terms

Biological Process

GO:0044659 cytolysis by virus of host cell
GO:0009253 peptidoglycan catabolic process
GO:0019076 viral release from host cell

Molecular Function

GO:0003796 lysozyme activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
  • cd00736 (bacteriophage_lambda_lysozyme)
HAMAP