Atypical kinase COQ8A (IPR034640)

Short name: COQ8A

Overlapping homologous superfamilies


Family relationships



The UbiB family has five mammalian members (ADCK1-5), which are classified as atypical kinases. COQ8A (ADCK3) is an UbiB protein associated with ubiquinone (Coenzyme Q, CoQ) biosynthesis and ataxia [PMID: 18319074]. Although COQ8A was predicted to be a protein kinase, it lacks canonical protein kinase activity [PMID: 25498144, PMID: 27499294]. Instead, COQ8A has ATPase activity and interacts with lipid CoQ intermediates [PMID: 27499294].

GO terms

Biological Process

GO:0006744 ubiquinone biosynthetic process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005739 mitochondrion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.