Galactarate dehydratase 3 (IPR034623)

Short name: Galactarate_dehydratase_3

Overlapping homologous superfamilies

Family relationships


This entry includes galactarate dehydratase III (A9CG74) from Agrobacterium tumefaciens C58. It catalyzes the dehydration of m-galactarate to 2-keto-3-deoxy-galactarate, as part of the synthesis of alpha-ketoglutarate. It has also been shown to convert D-galacturonate to 3-deoxy-D-xylo-hexarate or 3-deoxy-D-lyxo-hexarate, an unexpected reaction for an enolase superfamily member, because it involves abstraction of a proton alpha to an aldehyde group rather than a proton alpha to a carboxylate group [PMID: 24926996].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.