Pathways & interactions
Probable RNA-binding protein 46, RNA recognition motif 2 (IPR034435)
Short name: RBM46_RRM2
Overlapping homologous superfamilies
- Nucleotide-binding alpha-beta plait domain superfamily (IPR012677)
- RNA-binding domain superfamily (IPR035979)
- RNA recognition motif domain (IPR000504)
- Probable RNA-binding protein 46, RNA recognition motif 2 (IPR034435)
This entry represents the RNA recognition motif 2 (RRM2) of RBM46.
RBM46 is also termed cancer/testis antigen 68 (CT68), a putative RNA-binding protein that shows high sequence homology with heterogeneous nuclear ribonucleoprotein R (hnRNP R) and heterogeneous nuclear ribonucleoprotein Q (hnRNP Q). Its biological function remains unclear. It has been shown to bind to and stabilize Cdx2 mRNA in early mouse embryos [PMID: 25397698]. Like hnRNP R and hnRNP Q, RBM46 contains two well-defined and one degenerated RNA recognition motifs (RRMs).
- cd12492 (RRM2_RBM46)