Domain

Probable RNA-binding protein 46, RNA recognition motif 2 (IPR034435)

Short name: RBM46_RRM2

Overlapping homologous superfamilies

Domain relationships

Description

This entry represents the RNA recognition motif 2 (RRM2) of RBM46.

RBM46 is also termed cancer/testis antigen 68 (CT68), a putative RNA-binding protein that shows high sequence homology with heterogeneous nuclear ribonucleoprotein R (hnRNP R) and heterogeneous nuclear ribonucleoprotein Q (hnRNP Q). Its biological function remains unclear. It has been shown to bind to and stabilize Cdx2 mRNA in early mouse embryos [PMID: 25397698]. Like hnRNP R and hnRNP Q, RBM46 contains two well-defined and one degenerated RNA recognition motifs (RRMs).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD