Pathways & interactions
Prp24, RNA recognition motif1 (IPR034397)
Short name: Prp24_RRM1
Overlapping homologous superfamilies
- Nucleotide-binding alpha-beta plait domain superfamily (IPR012677)
- RNA-binding domain superfamily (IPR035979)
- RNA recognition motif domain (IPR000504)
- Prp24, RNA recognition motif1 (IPR034397)
This entry represents the RNA recognition motif 1 (RRM1) of Prp24.
Prp24 is an RNA-binding protein with four well conserved RNA recognition motifs (RRMs). It facilitates U6 RNA base-pairing with U4 RNA during spliceosome assembly [PMID: 21653550]. Prp24 specifically binds free U6 RNA primarily with RRM 1 and 2 and facilitates pairing of U6 RNA bases with U4 RNA bases [PMID: 20181740, PMID: 15811912].
- cd12296 (RRM1_Prp24)