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Overview
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Pathways & interactions
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Structures
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Cross-references
Domain
Nop13/Rnp24, RNA recognition motif 1 (IPR034225)
Short name: Nop13/Rnp24_RRM1
Overlapping homologous superfamilies
- Nucleotide-binding alpha-beta plait domain superfamily (IPR012677)
- RNA-binding domain superfamily (IPR035979)
Domain relationships
- RNA recognition motif domain (IPR000504)
- Nop13/Rnp24, RNA recognition motif 1 (IPR034225)
Description
This entry represents the RNA recognition motif 1 (RRM1) of Nop13p from Saccharomyces cerevisiae. It shares high sequence similarity with nucleolar protein 12 (Nop12p). Neither Nop12p nor Nop13p are essential for growth. However, unlike Nop12p that is localized to the nucleolus, Nop13p localizes primarily to the nucleolus but is also present in the nucleoplasm to a lesser extent. Nop13p contains two RNA recognition motifs (RRMs) [PMID: 11452019]. Proteins containing this domain include Rnp24 from S. pombe.
Contributing signatures
Signatures from InterPro member databases are used to construct an entry.
CDD
- cd12396 (RRM1_Nop13p_fungi)